[an error occurred while processing this directive]<meta name="keywords" content="Department of Computer Science, publications, by date, Computational Physiology"></meta><meta name="description" content="Publications, by date,Computational Physiology, Department of Computer Science, Oxford"></meta><title>Department of Computer Science: Computational Physiology: Publications
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			</style>[an error occurred while processing this directive]<div class="content-width"><ol class="breadcrumb text-uppercase"><li><a href="/">Home</a></li><li><a href="/research/">Research</a></li><li><a href="/research/compbio/">Computational Biology and Health Informatics</a></li><li><a href="/research/compbio/activities.html">activities</a></li><li><a href="/activities/computationalphysiology/">Computational Physiology</a></li><li class="active">Publications</li></ol></div><!-- MOBILE NAVIGATION --><div class="content-width space-below mobile-menu-placeholder visible-xs visible-sm"></div><!-- COLUMNS --><div class="container-fluid content-width"><div class="row"><div class="col-xs-12 col-md-9 col-md-push-3" id="maincontent"><!-- CONTENT (Column 2) --><div class="page-title"><h1>Computational Physiology: Publications
</h1></div><div role="toolbar" class="btn-toolbar"><div class="btn-group"><a href="/activities/publications/date/computationalphysiology.html" aria-hidden="true" type="button" class="btn btn-oxford-blue"><span class="glyphicon glyphicon-sort-by-attributes"></span> By date</a><a href="/activities/publications/title/computationalphysiology.html" aria-hidden="true" type="button" class="btn btn-default"><span class="glyphicon glyphicon-sort-by-attributes"></span> By title</a><a href="/activities/publications/type/computationalphysiology.html" aria-hidden="true" type="button" class="btn btn-default"><span class="glyphicon glyphicon-sort-by-attributes"></span> By type</a><a href="/activities/publications/bibtex/computationalphysiology.html" aria-hidden="true" type="button" class="btn btn-default"><span class="glyphicon glyphicon-file"></span> BibTex</a></div></div><ul class="list-unbulleted list-unbulleted-spaced"><li>
	
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	<p class="publicationTitle"> <strong>
            Control of NFAT Isoform Activation and NFAT&#x2212;Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals </strong> </p>
	    <p class="publicationAuthors"> <em> P Kar&#x201a; GR Mirams&#x201a; HC Christian and AB Parekh  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Molecular Cell</em>.
        
            Vol. 64.
        
            No. 4.
        
                Pages 746&#x2212;759.
            2016.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication10781-abstract.html">
			Details <span class="sr-only" > about <em> Control of NFAT Isoform Activation and NFAT&#x2212;Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals  </em></span> </a> |
			<a href="/publications/publication10781.bib">
			BibTeX  <span class="sr-only" > data for <em> Control of NFAT Isoform Activation and NFAT&#x2212;Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1016/j.molcel.2016.11.011">
		DOI (10.1016/j.molcel.2016.11.011)
		</a> 
					| <a href="http://www.sciencedirect.com/science/article/pii/S1097276516307195"> Link <span class="sr-only" > to <em> Control of NFAT Isoform Activation and NFAT&#x2212;Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Hierarchical Bayesian inference for ion channel screening dose&#x2212;response data [version 1; referees: awaiting peer review] </strong> </p>
	    <p class="publicationAuthors"> <em> RH Johnstone&#x201a; R Bardenet&#x201a; DJ Gavaghan and GR Mirams  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Wellcome Open Research</em>.
        
            Vol. 1.
        
                Pages 6.
            2016.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication10776-abstract.html">
			Details <span class="sr-only" > about <em> Hierarchical Bayesian inference for ion channel screening dose&#x2212;response data [version 1; referees: awaiting peer review]  </em></span> </a> |
			<a href="/publications/publication10776.bib">
			BibTeX  <span class="sr-only" > data for <em> Hierarchical Bayesian inference for ion channel screening dose&#x2212;response data [version 1; referees: awaiting peer review]  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.12688/wellcomeopenres.9945.1">
		DOI (10.12688/wellcomeopenres.9945.1)
		</a> 
					| <a href="https://wellcomeopenresearch.org/articles/1-6/v1"> Link <span class="sr-only" > to <em> Hierarchical Bayesian inference for ion channel screening dose&#x2212;response data [version 1; referees: awaiting peer review]  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology </strong> </p>
	    <p class="publicationAuthors"> <em> GR Mirams&#x201a; P Pathmanathan&#x201a; RA Gray&#x201a; P Challenor and RH Clayton  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Journal of Physiology</em>.
        2016.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication10343-abstract.html">
			Details <span class="sr-only" > about <em> White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology  </em></span> </a> |
			<a href="/publications/publication10343.bib">
			BibTeX  <span class="sr-only" > data for <em> White Paper: Uncertainty and variability in computational and mathematical models of cardiac physiology  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1113/JP271671">
		DOI (10.1113/JP271671)
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	<p class="publicationTitle"> <strong>
            Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart </strong> </p>
	    <p class="publicationAuthors"> <em> VM Mahoney&#x201a; V Mezzano&#x201a; GR Mirams&#x201a; K Maass&#x201a; Z Li&#x201a; M Cerrone&#x201a; C Vasquez&#x201a; A Bapat&#x201a; M Delmar and GE Morley  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Scientific Reports</em>.
        
            Vol. 6.
        
                Pages 26744.
            2016.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication10455-abstract.html">
			Details <span class="sr-only" > about <em> Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart  </em></span> </a> |
			<a href="/publications/publication10455.bib">
			BibTeX  <span class="sr-only" > data for <em> Connexin 43 contributes to electrotonic conduction across scar tissue in the intact heart  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1038/srep26744">
		DOI (10.1038/srep26744)
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	<p class="publicationTitle"> <strong>
            White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century. </strong> </p>
	    <p class="publicationAuthors"> <em> AP Hill&#x201a; MD Perry&#x201a; N Abi&#x2212;Gerges&#x201a; J&#x2212;P Couderc&#x201a; B Fermini&#x201a; JC Hancox&#x201a; BC Knollmann&#x201a; GR Mirams&#x201a; J Skinner&#x201a; W Zareba and JI Vandenberg  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Journal of Physiology</em>.
        2016.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication10454-abstract.html">
			Details <span class="sr-only" > about <em> White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century.  </em></span> </a> |
			<a href="/publications/publication10454.bib">
			BibTeX  <span class="sr-only" > data for <em> White Paper: Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21st Century.  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1113/JP272015">
		DOI (10.1113/JP272015)
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	<p class="publicationTitle"> <strong>
            Recent developments in using mechanistic cardiac modelling for drug safety evaluation </strong> </p>
	    <p class="publicationAuthors"> <em> MR Davies&#x201a; K Wang&#x201a; GR Mirams&#x201a; A Caruso&#x201a; D Noble&#x201a; A Walz&#x201a; T Lav&#xe9;&#x201a; F Schuler&#x201a; T Singer and L Polonchuk  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Drug Discovery Today</em>.
        
            Vol. 21.
        
            No. 6.
        
                Pages 924&#x2013;938.
            2016.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication10453-abstract.html">
			Details <span class="sr-only" > about <em> Recent developments in using mechanistic cardiac modelling for drug safety evaluation  </em></span> </a> |
			<a href="/publications/publication10453.bib">
			BibTeX  <span class="sr-only" > data for <em> Recent developments in using mechanistic cardiac modelling for drug safety evaluation  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1016/j.drudis.2016.02.003">
		DOI (10.1016/j.drudis.2016.02.003)
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	<p class="publicationTitle"> <strong>
            The Cardiac Electrophysiology Web Lab </strong> </p>
	    <p class="publicationAuthors"> <em> Jonathan Cooper&#x201a; Martin Scharm and Gary Mirams  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Biophysical Journal</em>.
        
            Vol. 110.
        
            No. 2.
        
                Pages 292&#x2212;300.
            2016.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication10258-abstract.html">
			Details <span class="sr-only" > about <em> The Cardiac Electrophysiology Web Lab  </em></span> </a> |
			<a href="/publications/publication10258.bib">
			BibTeX  <span class="sr-only" > data for <em> The Cardiac Electrophysiology Web Lab  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1016/j.bpj.2015.12.012">
		DOI (10.1016/j.bpj.2015.12.012)
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	<p class="publicationTitle"> <strong>
            Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models? </strong> </p>
	    <p class="publicationAuthors"> <em> RH Johnstone&#x201a; ET Chang&#x201a; R Bardenet&#x201a; TP de Boer&#x201a; DJ Gavaghan&#x201a; P Pathmanathan&#x201a; RH Clayton and GR Mirams  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Journal of Molecular and Cellular Cardiology</em>.
        
            Vol. 96.
        
                Pages 49&#x2212;62.
            2016.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication10154-abstract.html">
			Details <span class="sr-only" > about <em> Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models?  </em></span> </a> |
			<a href="/publications/publication10154.bib">
			BibTeX  <span class="sr-only" > data for <em> Uncertainty and variability in models of the cardiac action potential: can we build trustworthy models?  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1016/j.yjmcc.2015.11.018">
		DOI (10.1016/j.yjmcc.2015.11.018)
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	<p class="publicationTitle"> <strong>
            Cardiac Tissue Slices: Preparation&#x201a; Handling&#x201a; and Successful Optical Mapping </strong> </p>
	    <p class="publicationAuthors"> <em> K Wang&#x201a; P Lee&#x201a; GR Mirams&#x201a; P Sarathchandra&#x201a; T Borg&#x201a; DJ Gavaghan&#x201a; P Kohl and C Bollensdorff  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>American Journal of Physiology: Heart and Circulatory Physiology</em>.
        
            Vol. 308.
        
                Pages H1112&#x2212;H1125.
            2015.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication9289-abstract.html">
			Details <span class="sr-only" > about <em> Cardiac Tissue Slices: Preparation&#x201a; Handling&#x201a; and Successful Optical Mapping  </em></span> </a> |
			<a href="/publications/publication9289.bib">
			BibTeX  <span class="sr-only" > data for <em> Cardiac Tissue Slices: Preparation&#x201a; Handling&#x201a; and Successful Optical Mapping  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1152/ajpheart.00556.2014">
		DOI (10.1152/ajpheart.00556.2014)
		</a> 
					| <a href="http://ajpheart.physiology.org/content/308/9/H1112"> Link <span class="sr-only" > to <em> Cardiac Tissue Slices: Preparation&#x201a; Handling&#x201a; and Successful Optical Mapping  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            A web portal for in&#x2212;silico action potential predictions </strong> </p>
	    <p class="publicationAuthors"> <em> Geoff Williams and Gary Mirams  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Journal of Pharmacological and Toxicological Methods</em>.
        
            Vol. 75.
        
                Pages 10&#x2212;16.
            2015.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication9544-abstract.html">
			Details <span class="sr-only" > about <em> A web portal for in&#x2212;silico action potential predictions  </em></span> </a> |
			<a href="/publications/publication9544.bib">
			BibTeX  <span class="sr-only" > data for <em> A web portal for in&#x2212;silico action potential predictions  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1016/j.vascn.2015.05.002">
		DOI (10.1016/j.vascn.2015.05.002)
		</a> 
					| <a href="http://dx.doi.org/10.1016/j.vascn.2015.05.002"> Link <span class="sr-only" > to <em> A web portal for in&#x2212;silico action potential predictions  </em></span> </a>
  				
		
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